Dr. Melvin Bonilla Felix completed his Medical School and Pediatric Training at the University of Puerto Rico and then moved to Washington University in Saint Louis, MO for his Pediatric Nephrology Fellowship. For 7 years worked at University of Texas-Houston Health Science Center, where he was the Program Director for the Fellowship Program and Director of the Pediatric Peritoneal Dialysis Program. In 1999 he returned to his beloved Puerto Rico, where he currently occupies the position of Chair of the Department of Pediatrics. He served in the IPNA Council from 2007-2013 and is the President ALANEPE (Latin American Association of Pediatric Nephrology).
Joseph Flynn, MD, MS, holds the Dr. Robert O. Hickman Endowed Chair in Pediatric Nephrology. Dr. Flynn completed his pediatric nephrology training at St. Christopher’s Hospital for Children in Philadelphia, PA, and later received an MS in Clinical Research from the Albert Einstein College of Medicine, Bronx, NY. During his fellowship training, Dr. Flynn obtained experience in clinical research under the guidance of Bruce Kaiser, MD, and worked in the laboratory of Dr. Bonita Falkner at the Medical College of Pennsylvania. He has developed specialized expertise in the treatment of childhood hypertension and has published extensively in this area, including several publications as the lead investigator of industry-sponsored clinical trials. More recently, he has established an interest in cardiovascular complications of chronic kidney disease in children and is a lead investigator in the NIH-sponsored CKiD cohort study, which focuses on cardiovascular disease in this population. Dr. Flynn has served as a research mentor to numerous pediatric nephrology trainees who now hold faculty positions at other academic institutions. Additionally, he has served on the Working Group of the National High Blood Pressure Education Program, is the immediate past-president of the American Society of Pediatric Nephrology and is the chair of a new American Academy of Pediatrics committee charged with developing updated guidelines for childhood hypertension.
I am an experienced clinician with a broad background in pediatric nephrology, but have cultivated my career in the subfields of critical care nephrology, nutrition and transplant management, vasculitis, and pioneered the original work in pediatric renal replacement therapy. I have served on various NIH review boards and study sections, and have been awarded prior NIH and private grants as principal investigator for clinical research in these fields. Specific to this grant application, in 2009 we published clinical research on the improvement of neonatal acute kidney injury with uric acid lowering agents. In addition, during my early basic science career my area of research was on endothelial dysfunction which relates to uric acid effects on the vascular endothelium. I lecture extensively throughout the world on these topics and have assisted the training and development of pediatric nephrology programs around the country and internationally. Specifically, I have been an invited speaker in areas of AKI, Renal Replacement Therapy and Transplantation in Russia, Egypt, Turkey, UAE, South Africa, Germany, Italy, Belgium, UK, Portugal, Chile, Brazil, Costa Rica, Mexico, Canada and the US.
I am the founder and chairman of a bi-annual meeting of the International Pediatric Continuous Renal Replacement Therapy and have an active web site at www.pcrrt.com for this information and am considered the pioneer and leader in the area of pediatric continuous renal replacement therapy and critical care nephrology. I have successfully mentored clinicians and clinician scientists, and am a reviewer for greater than 30 separate medical journals, have authored greater than 140 manuscripts and greater than 40 book chapters. My experience both clinically and through my own research enables me to serve as a clinical principal investigator and mentor on this U24 grant application. I have been an invited speaker in areas of AKI, Renal Replacement Therapy and Transplantation in Russia, Egypt, Turkey, UAE, South Africa, Germany, Italy, Belgium, UK, Portugal, Chile, Brazil, Costa Rica, Mexico, Canada and the US.
John D Mahan, MD, is a Professor of Pediatrics at the Ohio State University College of Medicine (OSU COM), where he is Director of the Center for Faculty Development at Nationwide Children's Hospital (NCH) and the NCH representative in the OSU Center for FAME (Faculty Advancement, Mentoring, and Engagement) Executive Committee. He is the Program Director for the Pediatric Nephrology Fellowship Programs at Nationwide Children’s Hospital (NCH)/OSU, and Director, Metabolic Bone Clinic at NCH. He Co-Chairs the IPNA Profesisonal Educaiton Committee, Co-Chairs the ASPN Training Program Directors (TPD) Committee and is President of the Board of Directors of the Pediatric Nephrology Research Consortium. He Chairs the American Academy of Pediatrics Pedialink Editorial Board and Chairs the Faculty Development for Medical Educators online faculty development platform.
Dr. Mahan received his MD degree from Hahnemann University (now Drexel) and completed his Residency in Pediatrics (and served as Pediatric Chief Resident) and Fellowship in Pediatric Nephrology at the University of Minnesota. His research career has focused on efforts to define 1) the pathogenesis and treatment of glomerular disorders (GN, nephrotic syndrome, HUS), 2) best treatment practices in pediatric nephrology (including growth in children with CKD, metabolic bone disorders, nephrotic syndrome, hypertension), and 3) evidence-based innovations in medical education. He ipresently serves on the NIH CureGN Steering Committee and the NIH CKiD Growth Studies Sub-Committee. He participates in the Neonatal Kidney Collaborative and several medical education collaborative groups, including as Co-Chair of the Pediatric Resident Burnout-Resilience Study Consortium.
Dr. Maria Ferris is a Professor and epidemiologist at the University of North Carolina at Chapel Hill. Dr. Ferris directs the UNC STARx health care Transition and Self-management Program. She is also the co-founder of the International Health Care Transition Research Consortium and the International Pediatric Nephrology Fellows Conference.
Dr. Ferris’ mission is to improve the outcomes of adolescents and emerging adults with pediatric-onset chronic conditions as they transfer to adult-focused health services; with the use of evidence-based provider and patient tools. Dr. Ferris has numerous publications and has received numerous awards for her research, mentoring and advocacy activities.
Dr Miranda van Tilburg is an Associate Professor of Clinical Research at Campbell University, Adjunct Professor of Medicine at the University of North Carolina, and Affiliate Associate Professor of Social Work at the University of Washington. Dr van Tilburg is a health psychologist by training. Her research focuses on developing short, distance delivered behavioral treatments for childhood medical disorders. She has a special interest in helping parents manage their child’s diseases as well as preparing youth for independently managing their own symptoms. Her work has involved clinical trials to test parent-focused interventions to decrease child symptoms. She has over 200 publications in her name and has received funding from NIH, foundations and pharmaceutical companies.
Dr. Filler is Professor of Pediatrics, Medicine, and Pathology and Laboratory Medicine at the University of Western Ontario, where he serves as the division chief of Pediatric Nephrology. From 2006-2016, he served as Professor and Chair of the Department of Pediatrics at the University of Western Ontario and Chief of Pediatrics at the Children's Hospital, London Health Sciences Centre. Early in his career, Dr. Filler sought international experience and spent a year in Phoenix, Arizona, where he completed High School. He earned his undergraduate and medical degrees from Hannover Medical School in Germany and completed his specialty training in Pediatrics at the same institution. In 1988 he won a prestigious scholarship of the “Deutsche Forschungsgemeinschaft” - German equivalent to the CIHR - and spent part of the subspecialty training and research at the Hospital for Sick Children at Great Ormond Street in London, UK. After his return to Germany in 1990, he became a consult pediatric nephrologist and worked in Hannover and Berlin. He completed a PhD in clinical pharmacology at the Charité Hospital, Humboldt University at Berlin, and promoted to Associate Professor. In 1997, Dr. Filler became acting head of the Division of Pediatric Nephrology at the Charité, where he was able to serve as the principal investigator of the first published randomized controlled clinical trial in pediatric transplantation, comparing Cyclosporine Microemulsion and Tacrolimus. In 1999, Dr. Filler assumed the role as Chief of the Division of Nephrology at the Children's Hospital of Eastern Ontario (CHEO) in Ottawa and was promoted to Professor in 1999. He has authored over 300 papers in peer-reviewed journals. His research interests include drug disposition in children and adolescents as well as research on improving outcomes of children with chronic kidney disease, dialysis and transplantation.